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Ecopipam

Product Specifications

CAS Number

112108-01-7

Target

5-HT Receptor, Dopamine Receptor, Adrenergic Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Purity

0.9968

Bioactivity

Ecopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam demonstrates more than 40-fold selectivity over D2, D4, 5-HT, and α2a receptors (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively) . It is used in research on schizophrenia and obesity.

Smiles

CN1[C@@]2([C@@](C=3C(=CC(Cl)=C(O)C3)CC1)(C=4C(CC2)=CC=CC4)[H])[H]

Molecular Formula

C19H20ClNO

Molecular Weight

313.82

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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