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Pinometostat

Product Specifications

CAS Number

1380288-87-8

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9986

Bioactivity

Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor (Ki=80 pM) . Pinometostat has antitumor activity and can be used in experiments to study a variety of leukemia treatments.

Smiles

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN(C(C)C)[C@H]4C[C@@H](CCC=5NC=6C(N5)=CC=C(C(C)(C)C)C6)C4)[C@H]1O

Molecular Formula

C30H42N8O3

Molecular Weight

562.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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