Nigericin sodium salt
Product Specifications
CAS Number
28643-80-3
Target
NOD, NOD-like Receptor (NLR), Pyroptosis, Potassium Channel, Antibiotic, Wnt/beta-catenin, Antibacterial
Related Pathways
Membrane transporter/Ion channel, NF-κB, Immunology/Inflammation, Apoptosis, Stem Cells, Cytoskeletal Signaling, Microbiology/Virology
Purity
0.9952
Bioactivity
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-positive bacteria.
Smiles
[Na+].[H][C@@]1(C[C@H](C)[C@@]([H])(O1)[C@]1(C)CC[C@@]([H])(O1)[C@]1(C)C[C@@H](C)[C@]2(O1)O[C@]([H])(C[C@@]1([H])CC[C@H](C)[C@@]([H])(O1)[C@@H](C)C([O-])=O)C[C@@H](OC)[C@H]2C)[C@@]1([H])O[C@@](O)(CO)[C@H](C)C[C@@H]1C
Molecular Formula
C40H67NaO11
Molecular Weight
746.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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