CGP77675 hydrate
Product Specifications
Target
Src|||Others
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Others
Bioactivity
CGP77675 hydrate is an orally active, potent inhibitor of Src family kinases. It inhibits the phosphorylation of peptide substrates and autophosphorylation of purified Src (IC50: 5-20 and 40 nM, respectively), as well as Src, EGFR, KDR, v-Abl, and Lck with IC50s of 0.02, 0.15, 1.0, 0.31, and 0.29 ?M, respectively. CGP77675 hydrate may be useful for treating diseases associated with elevated bone loss and has anticancer activity [1].
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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