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CGP77675

Product Specifications

CAS Number

234772-64-6

Target

Bcr-Abl, Src, EGFR, VEGFR

Related Pathways

JAK/STAT signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9966

Bioactivity

CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and autophosphorylation of purified Src. CGP77675 exhibits anticancer activity.

Smiles

NC1=C2C(=CN(C2=NC=N1)C3=CC=C(CCN4CCC(O)CC4)C=C3)C5=CC(OC)=CC=C5

Molecular Formula

C26H29N5O2

Molecular Weight

443.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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