SGC0946
Product Specifications
CAS Number
1561178-17-3
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9982
Bioactivity
SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM) ; selectively kill mixed lineage leukemia cells.
Smiles
CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12
Molecular Formula
C28H40BrN7O4
Molecular Weight
618.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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