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GSK1838705A

Product Specifications

CAS Number

1116235-97-2

Target

JNK, ALK, IGF-1R, S6 Kinase

Related Pathways

MAPK, PI3K/Akt/mTOR signaling, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

>99.99%

Bioactivity

GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.

Smiles

CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12

Molecular Formula

C27H29FN8O3

Molecular Weight

532.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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