GSK1838705A
Product Specifications
CAS Number
1116235-97-2
Target
JNK, ALK, IGF-1R, S6 Kinase
Related Pathways
MAPK, PI3K/Akt/mTOR signaling, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.
Smiles
CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12
Molecular Formula
C27H29FN8O3
Molecular Weight
532.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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