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XL019

Product Specifications

CAS Number

945755-56-6

Target

PDGFR, Apoptosis, FLT, JAK

Related Pathways

Apoptosis, Stem Cells, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic

Purity

0.9923

Bioactivity

XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.

Smiles

O=C(Nc1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1)[C@@H]1CCCN1

Molecular Formula

C25H28N6O2

Molecular Weight

444.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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