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AT9283

Product Specifications

CAS Number

896466-04-9

Target

FLT, Apoptosis, Autophagy, JAK, Aurora Kinase, Bcr-Abl

Related Pathways

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Autophagy, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells, Angiogenesis, Chromatin/Epigenetic, Apoptosis

Purity

0.9998

Bioactivity

AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2 (IC50=1.2 nM) and JAK3 (IC50=1.1 nM), Aurora A, Aurora B and Abl (T315I) .

Smiles

O=C(NC1CC1)Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1

Molecular Formula

C19H23N7O2

Molecular Weight

381.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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