Lorlatinib
Product Specifications
CAS Number
1454846-35-5
Target
ROS Kinase, Apoptosis, ROS, ALK, Tyrosine Kinases
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Immunology/Inflammation, Apoptosis
Purity
0.9995
Bioactivity
Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.
Smiles
C[C@H]1Oc2cc(cnc2N)-c2c(CN(C)C(=O)c3ccc(F)cc13)nn(C)c2C#N
Molecular Formula
C21H19FN6O2
Molecular Weight
406.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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