BMS-695735
Product Specifications
CAS Number
1054315-48-8
Target
Others, IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
BMS-695735, a benzimidazole inhibitor of insulin-like growth factor-1 receptor, has broad-spectrum antitumor activity in vivo. It was found that BMS-695735 had strong inhibition of CYP3A4, induction of CYP3A4 mediated by PXR transactivation, poor water solubility, and high plasma protein binding.
Smiles
N(CCN1C=C(Cl)C=N1)C2=C(C=3NC=4C(N3)=C(C)C=C(C4)C5CCN(CCCF)CC5)C(=O)NC=C2
Molecular Formula
C26H31ClFN7O
Molecular Weight
512.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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