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CZC-25146

Product Specifications

CAS Number

1191911-26-8

Target

PPAR, LRRK2

Related Pathways

Metabolism, DNA Damage/DNA Repair, Autophagy

Purity

0.982

Bioactivity

CZC-25146 (CHEMBL2397014) is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2 (Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.

Smiles

COc1cc(ccc1Nc1ncc(F)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1

Molecular Formula

C22H25FN6O4S

Molecular Weight

488.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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