TPCA-1
Product Specifications
CAS Number
507475-17-4
Target
Apoptosis, IκB/IKK, STAT
Related Pathways
NF-κB, JAK/STAT signaling, Apoptosis, Stem Cells
Purity
0.9929
Bioactivity
TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM) ; shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.
Smiles
NC(=O)Nc1sc(cc1C(N)=O)-c1ccc(F)cc1
Molecular Formula
C12H10FN3O2S
Molecular Weight
279.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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