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TPCA-1

Product Specifications

CAS Number

507475-17-4

Target

Apoptosis, IκB/IKK, STAT

Related Pathways

NF-κB, JAK/STAT signaling, Apoptosis, Stem Cells

Purity

0.9929

Bioactivity

TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM) ; shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.

Smiles

NC(=O)Nc1sc(cc1C(N)=O)-c1ccc(F)cc1

Molecular Formula

C12H10FN3O2S

Molecular Weight

279.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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