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Ruxolitinib phosphate

Product Specifications

CAS Number

1092939-17-7

Target

Autophagy, Mitophagy, JAK

Related Pathways

Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Autophagy, Angiogenesis

Purity

>99.99%

Bioactivity

Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Its selectivity for JAK1/2 is more than 130 times that of JAK3.

Smiles

OP(O)(O)=O.N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12

Molecular Formula

C17H21N6O4P

Molecular Weight

404.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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