Deoxycorticosterone acetate
Product Specifications
CAS Number
56-47-3
Target
Endogenous Metabolite, Glucocorticoid Receptor, Adrenergic Receptor
Related Pathways
Neuroscience, GPCR/G Protein, Endocrinology/Hormones, Metabolism
Purity
>99.99%
Bioactivity
Deoxycorticosterone acetate (DOCA) is a steroid hormone produced by the adrenal glands, possessing mineralocorticoid activity and serving as a precursor to aldosterone. As an agonist of the mineralocorticoid receptor, DOCA can induce severe kidney damage, including inflammation, fibrosis, glomerular injury, and proteinuria. It is commonly used to establish animal models of chronic kidney injury and hypertension.
Smiles
[H][C@@]12CC[C@H](C(=O)COC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
Molecular Formula
C23H32O4
Molecular Weight
372.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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