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Deoxycorticosterone acetate

Product Specifications

CAS Number

56-47-3

Target

Endogenous Metabolite|||Glucocorticoid Receptor|||Adrenergic Receptor

Related Pathways

Neuroscience|||GPCR/G Protein|||Endocrinology/Hormones|||Metabolism

Purity

>99.99%

Bioactivity

Deoxycorticosterone acetate (DOCA) is a steroid hormone produced by the adrenal glands, possessing mineralocorticoid activity and serving as a precursor to aldosterone. As an agonist of the mineralocorticoid receptor, DOCA can induce severe kidney damage, including inflammation, fibrosis, glomerular injury, and proteinuria. It is commonly used to establish animal models of chronic kidney injury and hypertension.

Smiles

[H][C@@]12CC[C@H](C(=O)COC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

Molecular Formula

C23H32O4

Molecular Weight

372.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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