A 83-01
Product Specifications
CAS Number
909910-43-6
Target
ALK, TGF-beta/Smad
Related Pathways
Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors
Purity
0.9876
Bioactivity
A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM) . A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures.
Smiles
Cc1cccc(n1)-c1nn(cc1-c1ccnc2ccccc12)C(=S)Nc1ccccc1
Molecular Formula
C25H19N5S
Molecular Weight
421.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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