AZD-5672
Product Specifications
CAS Number
780750-65-4
Target
CCR|||P-gp|||Potassium Channel
Related Pathways
Membrane transporter/Ion channel|||Neuroscience|||Microbiology/Virology|||GPCR/G Protein|||Immunology/Inflammation
Purity
0.981
Bioactivity
AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7.3 ?M and 32 ?M. AZD-5672 can be used in studies about rheumatoid arthritis.
Smiles
CCN(C1CCN(CC[C@H](c2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(F)c2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O
Molecular Formula
C32H38F2N2O5S2
Molecular Weight
632.78
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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