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AZD 7009

Product Specifications

CAS Number

335619-18-6

Target

Sodium Channel, Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9851

Bioactivity

AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, and prolonged E-4031-induced action potential duration, promoting early post-depolarization of Purkinye fibers (EADs) .

Smiles

C([C@@H](COC1=CC=C(C#N)C=C1)O)N2CC3OC(C2)CN(CCNC(OC(C)(C)C)=O)C3

Molecular Formula

C23H34N4O5

Molecular Weight

446.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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