AZD 7009
Product Specifications
CAS Number
335619-18-6
Target
Sodium Channel, Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9851
Bioactivity
AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, and prolonged E-4031-induced action potential duration, promoting early post-depolarization of Purkinye fibers (EADs) .
Smiles
C([C@@H](COC1=CC=C(C#N)C=C1)O)N2CC3OC(C2)CN(CCNC(OC(C)(C)C)=O)C3
Molecular Formula
C23H34N4O5
Molecular Weight
446.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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