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Olaparib

Product Specifications

CAS Number

763113-22-0

Target

PARP|||Autophagy|||Mitophagy

Related Pathways

Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Autophagy

Purity

>99.99%

Bioactivity

Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 ?M), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.

Smiles

C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3

Molecular Formula

C24H23FN4O3

Molecular Weight

434.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/37EED8E7-DF12-4E44-AF87-FE5EF4A2F443/T3015

Available Sizes

Curated Selection

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