Olaparib
Product Specifications
CAS Number
763113-22-0
Target
PARP|||Autophagy|||Mitophagy
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Autophagy
Purity
>99.99%
Bioactivity
Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 ?M), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.
Smiles
C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3
Molecular Formula
C24H23FN4O3
Molecular Weight
434.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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