Olaparib

Product Specifications

CAS Number

763113-22-0

Target

PARP|||Autophagy|||Mitophagy

Related Pathways

Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Autophagy

Purity

>99.99%

Bioactivity

Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 ?M), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.

Smiles

C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3

Molecular Formula

C24H23FN4O3

Molecular Weight

434.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

OM620015 96 Strip Well

Bovine Uncharacterized Protein C1orf54 (C1ORF54) ELISA Kit

Ask

View Details

FAB6577F 0.1 mL

Mouse Monoclonal CD44 Antibody (740017) [FITC]

Ask

View Details

TRC-A609985-100G 100 g

6-Aminohexanoic Acid

Ask

View Details