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Ponicidin

Product Specifications

CAS Number

52617-37-5

Target

JAK, STAT, Apoptosis

Related Pathways

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Apoptosis, Angiogenesis, JAK/STAT signaling

Purity

0.9992

Bioactivity

Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens that exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma cells, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on the protein levels of JAK2 and STAT3.

Smiles

[H][C@]12CC[C@]3([H])[C@]4(C(=O)C1=C)[C@@]2([H])O[C@@]1([H])O[C@]4(O)[C@@H](O)[C@]2([H])C(C)(C)CC[C@H](O)C312

Molecular Formula

C20H26O6

Molecular Weight

362.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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