Ponicidin
Product Specifications
CAS Number
52617-37-5
Target
JAK|||STAT|||Apoptosis
Related Pathways
Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Stem Cells|||Apoptosis|||Angiogenesis|||JAK/STAT signaling
Purity
0.9992
Bioactivity
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens that exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma cells, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on the protein levels of JAK2 and STAT3.
Smiles
[H][C@]12CC[C@]3([H])[C@]4(C(=O)C1=C)[C@@]2([H])O[C@@]1([H])O[C@]4(O)[C@@H](O)[C@]2([H])C(C)(C)CC[C@H](O)C312
Molecular Formula
C20H26O6
Molecular Weight
362.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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