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Daurinoline

Product Specifications

CAS Number

2831-75-6

Target

Histamine Receptor, Calcium Channel, 5-HT Receptor

Related Pathways

GPCR/G Protein, Immunology/Inflammation, Membrane transporter/Ion channel, Metabolism, Neuroscience

Bioactivity

Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury. Daurinoline could significantly reverse noradrenaline induced constriction of pial arterioles and venules, and increase the number of blood vessels which were decreased by noradrenaline.

Smiles

C([C@@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC4=CC=C(C[C@@H]5C=6C(=CC(O)=C(OC)C6)CCN5C)C=C4)=C(O)C=C3

Molecular Formula

C37H42N2O6

Molecular Weight

610.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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