AMG-628

Product Specifications

CAS Number

862269-73-6

Target

Others, TRP/TRPV Channel

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

AMG-628 is an effective and ATP-competitive RAF kinase inhibitor. AMG-628 has been shown to inhibit growth and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with B-RAFV600E mutations.

Smiles

O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)N4CCN(C(C)C5=CC=C(F)C=C5)CC4

Molecular Formula

C25H25FN6O2S

Molecular Weight

492.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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