AMG-628
Product Specifications
CAS Number
862269-73-6
Target
Others|||TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel|||Others
Bioactivity
AMG-628 is an effective and ATP-competitive RAF kinase inhibitor. AMG-628 has been shown to inhibit growth and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with B-RAFV600E mutations.
Smiles
O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)N4CCN(C(C)C5=CC=C(F)C=C5)CC4
Molecular Formula
C25H25FN6O2S
Molecular Weight
492.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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