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Beta-Sitosterol

Product Specifications

CAS Number

83-46-5

Target

Apoptosis, Lipase, Endogenous Metabolite

Related Pathways

Apoptosis, Metabolism

Purity

0.9995

Bioactivity

Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463), a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer. Although the exact mechanism of action of Beta-Sitosterol (SKF 14463) is unknown, it may be related to cholesterol metabolism or anti-inflammatory effects (via interference with prostaglandin metabolism) . Beta-Sitosterol (SKF 14463) induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells.

Smiles

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@H](C(C)C)CC)C)[H])[H]

Molecular Formula

C29H50O

Molecular Weight

414.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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