Phloretin
Product Specifications
CAS Number
60-82-2
Target
Endogenous Metabolite, SGLT, Urea Transporter, transporter
Related Pathways
Membrane transporter/Ion channel, GPCR/G Protein, Metabolism
Purity
>99.99%
Bioactivity
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.
Smiles
C(CCC1=CC=C(O)C=C1)(=O)C2=C(O)C=C(O)C=C2O
Molecular Formula
C15H14O5
Molecular Weight
274.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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