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Phloretin

Product Specifications

CAS Number

60-82-2

Target

Endogenous Metabolite, SGLT, Urea Transporter, transporter

Related Pathways

Membrane transporter/Ion channel, GPCR/G Protein, Metabolism

Purity

>99.99%

Bioactivity

Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.

Smiles

C(CCC1=CC=C(O)C=C1)(=O)C2=C(O)C=C(O)C=C2O

Molecular Formula

C15H14O5

Molecular Weight

274.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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