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WB403

Product Specifications

CAS Number

1594041-84-5

Target

Others, GPCR19

Related Pathways

Others, GPCR/G Protein

Bioactivity

WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores the normal distribution pattern of α-cell and β-cell in islets.

Smiles

C(OCC1=CC=C(Br)C=C1)C=2SC(=NC2C)C=3C=C(CC)N=CC3

Molecular Formula

C19H19BrN2OS

Molecular Weight

403.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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