VU0422288
Product Specifications
CAS Number
1630936-95-6
Target
GluR
Related Pathways
Neuroscience
Purity
0.9977
Bioactivity
VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus) .VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome (RTT) .
Smiles
Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1
Molecular Formula
C17H11Cl2N3O2
Molecular Weight
360.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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