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VRT-532

Product Specifications

CAS Number

38214-71-0

Target

CFTR

Related Pathways

Membrane transporter/Ion channel

Purity

>99.99%

Bioactivity

VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Modification of CFTR by this small molecule modulator can increase arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag), thus reducing the accumulation of 4-chondroitin sulfate in cystic fibrosis.

Smiles

CC1=CC=C(O)C(=C1)C1=NNC(=C1)C1=CC=CC=C1

Molecular Formula

C16H14N2O

Molecular Weight

250.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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