VRT-532
Product Specifications
CAS Number
38214-71-0
Target
CFTR
Related Pathways
Membrane transporter/Ion channel
Purity
>99.99%
Bioactivity
VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Modification of CFTR by this small molecule modulator can increase arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag), thus reducing the accumulation of 4-chondroitin sulfate in cystic fibrosis.
Smiles
CC1=CC=C(O)C(=C1)C1=NNC(=C1)C1=CC=CC=C1
Molecular Formula
C16H14N2O
Molecular Weight
250.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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