VPC-13163
Product Specifications
CAS Number
6637-10-1
Target
Androgen Receptor, Others
Related Pathways
Endocrinology/Hormones, Others
Purity
0.985
Bioactivity
VPC-13163 (NSC-52361) has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
Smiles
C=1(C=2C(NC1)=CC=CC2)C3CC=4C(N3)=CC=CC4
Molecular Formula
C16H14N2
Molecular Weight
234.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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