VA-K-14 hydrochloride
Product Specifications
CAS Number
1171341-19-7
Target
TSH Receptor
Related Pathways
GPCR/G Protein
Purity
0.9937
Bioactivity
VA-K-14 hydrochloride (VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
Smiles
Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1
Molecular Formula
C18H16ClN3S
Molecular Weight
341.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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