VA-K-14 hydrochloride
Product Specifications
CAS Number
1171341-19-7
Target
TSH Receptor
Related Pathways
GPCR/G Protein
Purity
0.9937
Bioactivity
VA-K-14 hydrochloride (VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
Smiles
Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1
Molecular Formula
C18H16ClN3S
Molecular Weight
341.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-52304R-FITC-TR 20 µL
Bcl-2 Recombinant Antibody, FITC Conjugated
Sign In for Pricing
View Details MBS6424143-01 0.1 mL
KPNA4 (Karyopherin alpha 4, Importin alpha 3, QIP1, SRP3, IPOA3) (APC)
Sign In for Pricing
View Details MBS6424143-02 5x 0.1 mL
KPNA4 (Karyopherin alpha 4, Importin alpha 3, QIP1, SRP3, IPOA3) (APC)
Sign In for Pricing
View Details