What is the catalog number for Tigilanol tiglate?

The catalog number for Tigilanol tiglate is T28975.

What sizes are available for Tigilanol tiglate?

Tigilanol tiglate is available in the following size(s): 25 mg.

Is Tigilanol tiglate in stock?

Tigilanol tiglate is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tigilanol tiglate?

Tigilanol tiglate is manufactured by Molfinity.

What is the estimated delivery time for Tigilanol tiglate?

Estimated delivery time for Tigilanol tiglate is approximately 10 business day(s), depending on your location.

Tigilanol tiglate

Product Specifications

CAS Number

943001-56-7

Target

PKC, Caspase

Related Pathways

Chromatin/Epigenetic, Proteases/Proteasome, Apoptosis, Cytoskeletal Signaling

Bioactivity

Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate promotes mitochondrial/endoplasmic reticulum dysfunction, leading to ATP depletion, caspase activation, and gasdermin E cleavage. It induces immunogenic cell death, enhancing the response to immune checkpoint blockade in both target tumours and non-injected tumours, resulting in tumour regression.

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