Thaspine acetate
Product Specifications
CAS Number
74578-01-1
Target
Others, Cytochromes P450, Bcl-2 Family, Apoptosis, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Others, Metabolism
Bioactivity
Thaspine acetate is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.
Smiles
CC(O)=O.COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31
Molecular Formula
C22H23NO8
Molecular Weight
429.425
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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