TDRL-551
Product Specifications
CAS Number
1644626-43-6
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9809
Bioactivity
TDRL-551 is a novel and potent replication protein A (RPA) inhibitor (IC50=18 μM) with potential anticancer activity.TDRL-551 inhibits RPA-DNA interaction and enhances the efficacy of platinum-based chemotherapy for lung and ovarian cancer.
Smiles
CCOc1ccc2cc(C3CC(=NN3C(=O)CCCC(O)=O)c3ccc(I)cc3)c(Cl)nc2c1
Molecular Formula
C25H23ClIN3O4
Molecular Weight
591.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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