T-1095A
Product Specifications
CAS Number
209746-56-5
Target
Others, Drug Metabolite
Related Pathways
Metabolism, Others
Bioactivity
T-1095A is an active metabolite of T-1095, a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs) . Chronic administration of T-1095 (0.1% w w (-1) pellet chow, for 12 weeks) decreased blood glucose and haemoglobin A (1C) levels, and improved glucose intolerance in db/db mice. Long-term treatment with T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
Smiles
C(CCC=1C=C2C(=CC1)OC=C2)(=O)C3=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C(C)C=C3O
Molecular Formula
C24H26O9
Molecular Weight
458.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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