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Suprafenacine

Product Specifications

CAS Number

1477482-50-0

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Purity

0.9991

Bioactivity

Suprafenacine (N'-[ (E) - (4-methylphenyl) methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.

Smiles

CC1=CC=C(\C=N\NC(=O)C2=NNC3=C2CCCC3)C=C1

Molecular Formula

C16H18N4O

Molecular Weight

282.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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