Suprafenacine
Product Specifications
CAS Number
1477482-50-0
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Purity
0.9991
Bioactivity
Suprafenacine (N'-[ (E) - (4-methylphenyl) methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.
Smiles
CC1=CC=C(\C=N\NC(=O)C2=NNC3=C2CCCC3)C=C1
Molecular Formula
C16H18N4O
Molecular Weight
282.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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