SJA6017
Product Specifications
CAS Number
190274-53-4
Target
Others|||Proteasome
Related Pathways
Ubiquitination|||Others|||Proteases/Proteasome
Bioactivity
SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 (IC50 = 78 nM) . SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM) . SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functional outcome.
Smiles
S(N[C@H](C(N[C@@H](CC(C)C)C=O)=O)[C@@H](C)C)(=O)(=O)C1=CC=C(F)C=C1
Molecular Formula
C17H25FN2O4S
Molecular Weight
372.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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