SI-2
Product Specifications
CAS Number
223788-33-8
Target
Others|||Apoptosis|||Src
Related Pathways
Apoptosis|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis
Purity
0.984
Bioactivity
SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1) . SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.
Smiles
CN1C=2C(N=C1NN=C(C)C3=CC=CC=N3)=CC=CC2
Molecular Formula
C15H15N5
Molecular Weight
265.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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