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SGE-516

Product Specifications

CAS Number

1430064-74-6

Target

Others, GABA Receptor

Related Pathways

Others, Neuroscience, Membrane transporter/Ion channel

Bioactivity

SGE516 is a neuroactive steroid and a positive allosteric modulator of both gamma- and delta-containing GABAA receptors. SGE516 reduces neuronal firing rates and epileptiform activity in vitro. SGE-516 protects against acute seizures and reduces neuronal cell death.

Smiles

C[C@@]12[C@]([C@]3([C@](CC1)([C@@]4([C@](CC3)(C[C@](C)(O)CC4)[H])[H])[H])[H])(CC[C@@H]2C(CN5N=CC=N5)=O)[H]

Molecular Formula

C23H35N3O2

Molecular Weight

385.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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