SGE-516
Product Specifications
CAS Number
1430064-74-6
Target
Others, GABA Receptor
Related Pathways
Others, Neuroscience, Membrane transporter/Ion channel
Bioactivity
SGE516 is a neuroactive steroid and a positive allosteric modulator of both gamma- and delta-containing GABAA receptors. SGE516 reduces neuronal firing rates and epileptiform activity in vitro. SGE-516 protects against acute seizures and reduces neuronal cell death.
Smiles
C[C@@]12[C@]([C@]3([C@](CC1)([C@@]4([C@](CC3)(C[C@](C)(O)CC4)[H])[H])[H])[H])(CC[C@@H]2C(CN5N=CC=N5)=O)[H]
Molecular Formula
C23H35N3O2
Molecular Weight
385.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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