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Setrobuvir

Product Specifications

CAS Number

1071517-39-9

Target

DNA/RNA Synthesis, SARS-CoV, HCV Protease

Related Pathways

Microbiology/Virology, Proteases/Proteasome, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

>99.99%

Bioactivity

Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s between 4 and 5 nM. setrobuvir shows good binding affinity for SARS-CoV-2 RdRp and induces inhibition of RdRp.

Smiles

C(N1[C@@]2([C@@]([C@@]3(C[C@]2(CC3)[H])[H])(C(O)=C(C1=O)C=4NC=5C(S(=O)(=O)N4)=CC(NS(C)(=O)=O)=CC5)[H])[H])C6=CC=C(F)C=C6

Molecular Formula

C25H25FN4O6S2

Molecular Weight

560.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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